The Milwaukee Brewers close out another home date at American Family Field on Saturday, September 26, 2026, squaring off against the St. Louis Cardinals at 7:10 PM ET. Milwaukee turns to right-hander Dustin May on the mound, while the Cardinals counter with young left-hander Quinn Mathews. With the regular season winding down and every game carrying weight in the standings, this is a divisional matchup that neither club can afford to treat casually. Catch it on Brewers.TV Presented by Potawatomi Sportsbook or on the radio at WTMJ 620 in Milwaukee.
Probable Starters: Dustin May vs. Quinn Mathews
Dustin May gets the ball for Milwaukee. The right-hander was acquired to add arm strength to a rotation that needs reliable depth, and Saturday night gives him a chance to deliver in a meaningful late-season divisional setting. May has the stuff to work through a Cardinals lineup, but his ability to get through innings efficiently will be the number to watch.
Quinn Mathews draws the start for St. Louis. The young left-hander represents the kind of pitching development the Cardinals have leaned on, and he brings a different look than Milwaukee hitters may be accustomed to seeing from the Cardinals staff. Getting a read on Mathews early — working counts and identifying his best pitch — will be critical for the Brewers offense to generate traffic.
Keys to Watch for the Brewers
- May's command and pitch efficiency: If May can establish his fastball early and keep the Cardinals off-balance through the middle innings, Milwaukee's bullpen won't be pressed into early service on a Saturday night.
- Offensive plate discipline against Mathews: Left-handed pitching can give Brewers hitters fits when they chase early. Working deep counts forces Mathews to show more of his arsenal and gives Milwaukee the best chance to do damage.
- Leverage situations in the late innings: Late-September divisional games frequently come down to one or two at-bats with runners in scoring position. How Milwaukee manages those moments — both on the mound and in the batter's box — will likely decide the outcome.
- Home crowd at American Family Field: A Saturday night home crowd in the final stretch of the regular season can be a genuine factor. The Brewers have an opportunity to use that energy.
Prediction
This one figures to be a tight, low-scoring affair. Both May and Mathews have the ability to keep runs off the board for stretches, which puts a premium on timely hitting. Milwaukee has the home-field advantage and the motivation of a late-season divisional game in front of their own fans. Give the edge to the Brewers, 3-2, in a game that goes deep into the bullpen for both clubs.
